Nutritional supplements such as probiotics and various enzyme preparations are very important to the health of modern people, but the preservation of these foods is more difficult than ordinary foods, so how can they be better preserved? Freeze-drying technology may become a widely used technology in the future. This technology is not only suitable for the food industry, but also for pharmaceuticals, beauty products and other industries.

　　Freeze drying technology helps the processing and production of nutritional supplements

　　In 2001, the Food and Agriculture Organization of the United Nations/World Health Organization (FAO/WHO) redefined probiotics as "living microorganisms in sufficient quantities that can have a beneficial effect on the health of the host". At present, the main types of probiotic products include solid beverages, compressed candies, soft candies, etc., but there are problems such as inconvenient consumption, or difficulty in maintaining the number of viable bacteria after opening. The freeze-drying technology that has emerged in recent years has solved the problem well. these puzzles.

　　Probiotics are mainly derived from lactic acid bacteria, bifidobacteria, streptococcus, and some yeasts with probiotic effects. The health effects of probiotics include maintaining the balance of intestinal microecology, inhibiting the growth and reproduction of pathogenic bacteria, improving the body's immunity, and promoting mineral absorption. The "Diagnosis and Treatment Plan for Novel Coronavirus Pneumonia (Trial Version 4)" jointly issued by the National Health Commission and the State Administration of Traditional Chinese Medicine on January 27, 2020 pointed out that "intestinal microecological regulators can be used to maintain intestinal Microecological balance, prevention of secondary bacterial infection".

　　Freeze-drying technology abandons the traditional preparation method of solid tablet molding, and the suspension made of active substances and a small amount of water-soluble excipients is subjected to low-temperature quick-freezing, liquid molding, and then freeze-drying, so that the water is directly sublimated from solid to gaseous state, forming Skeleton with loose pore structure. When the lyophilized orally disintegrating tablet containing this skeleton encounters a very small amount of water, the water molecules will enter every pore of the loose skeleton at an extremely fast speed, causing the raw materials to disintegrate and dissolve in an instant.

　　To sum up, freeze-drying is a new technology suitable for the processing and production of nutritional supplements, but there are still problems such as high processing costs, which will be the focus of future research.